"Endometriosis is a common gynecological disease. It is unique to have benign histology but
with malignant characteristics. Easy recurrence, multiple organ involvement and malignant
transformation potential make endometriosis a complex disease. Multi-factors contribute to
the pathophysiology. Recently, endometriosis has been regarded as a stem cell disease
(Sasson & Taylor, 2008). Some studies have provided evidence of the possible existence of
stem cells in endometrial tissue (Gargett et al., 2004, 2007). We successfully isolated eutopic
and ectopic endometrial mesenchymal stem cells (EN-MSCs) derived from one donor to
examine the genetic difference analysis that provided a powerful tool for investigating the
disease origin (Kao et al., 2011). Our results are consistent with the concept that
endometriosis is a stem cell disease."
http://cdn.intechopen.com/pdfs/36763/InTech-Stem_cell_as_the_novel_pathogenesis_of_endometriosis.pdf
